The built environment needs continuous adaptation to global population changes, the adverse effects of climate change, and evolving occupant requirements. To meet these evolving challenges, architects and engineers require access to high-fidelity design simulation tools to accurately predict complex behavior in buildings and cities. SimScale enables architects and engineers to integrate physics-based simulation into their entire design workflow starting from the earliest stages where critical design decisions are made. Rapid assessments of the microclimate impacts on design, for example, are now possible using the simple and intuitive workflow in SimScale. In this whitepaper, we discuss how SimScale, as a cloud-native engineering simulation platform, allows architects and engineers to simulate and analyze high-fidelity models with complex physics by making the practically infinite computational power of the cloud accessible, giving unprecedented accuracy in results, efficiency in design collaboration, and versatility in the vast range of products and applications that can be solved.