Boundary-condition strategy for liquid-cooled LPBF copper cold plates

I am structuring a conjugate heat-transfer model for a liquid-cooled cold plate made by laser powder bed fusion in copper alloy. The internal channels are as-built, so the measured inputs available for correlation are flow rate, pressure drop, inlet/outlet temperature, heat load, and the external contact-patch temperature.

This thermal design and validation workflow is the reference I am using to separate CFD inputs, measurable acceptance criteria, and test uncertainty.

My current sequence is:

  1. converge the hydraulic model against measured pressure drop before tuning heat-transfer assumptions;
  2. apply an effective channel roughness only within the measured range;
  3. compare both a uniform heat-flux patch and a mapped power-density boundary;
  4. correlate delta-T and thermal resistance at multiple flow points;
  5. keep material conductivity temperature-dependent and run a mesh-independence check near the walls.

For SimScale CHT, would you calibrate wall roughness first and then freeze it for the thermal runs, or solve hydraulic and thermal calibration together? I want to avoid a model that matches one operating point but has no predictive value.